Multiple system atrophy (MSA) is a disease characterised by α-synuclein inclusions that are present in the cytoplasm of oligodendrocytes. Watch this video to get an overview of pathology behind multiple system atrophy and the resultant clinical manifestations, diagnosis and treatment associated with it. Timeline: 0:00 - Basic characterstics and pathology associated with MSA 1:15 - Clinical manifestations 3:40 - Diagnosis 4:16 - Treatment 5:17 - Prognosis