Amyotrophic Lateral Sclerosis (ALS): Overview

Provided video explains the formation of neuronal inclusion bodies in ALS along with different mechanisms leading towards neuronal damage that include: glutamate mediated excitotoxicity, aggregation of mutant proteins to prions and release of damaging factors. Timeline: 0:00 - Introduction to ALS 1:03 - Formation of inclusion bodies and involved mutations 3:19 - Mechanism of neuronal damage in ALS