Desmosomes are specialized adhesive protein complexes that localize to intercellular junctions and are responsible for maintaining the mechanical integrity of tissues. This video focuses on the cell junctions specially desmosomes. 0:00 Introduction to Cell Connections 0:17 Spot Desmosomes 0:51 Belt Desmosomes 1:05 Gap Junctions 1:12 Connexon 1:20 Tight Junctions 1:34 Hemidesmosome