Kidneys pump around 400 gallons of recycled blood every day, throughout the day, the kidneys filter and produce around 1000 to 2000 milliliters of urine. So in general we excrete around 1.5 liter urine on an average in a single day. - Kidney disease can never be reversed. Its progression can only be slowed down. - High BP and diabetes can both lead to failure of kidneys. -When the kidney functions are completely lost, it is known as ESRD or End Stage Renal Disease.