images of your organs. These tests allow your doctor to look at your spinal cord, brain, and brainstem for evidence of the disease. Treatment options for neurosyphilis The antibiotic penicillin is used to treat syphilis and neurosyphilis. It may be injected or taken orally. The usual regimen lasts 10 to 14 days. The antibiotics probenecid and ceftriaxone are often used along with penicillin. Depending on your case, you may need to stay in the hospital while being treated. During your recovery, you’ll need blood tests at the three- and six-month marks. After that, you should have blood tests every year for three years following your treatment. Your doctor will continue to monitor your cerebrospinal fluid levels with spinal taps every six months. Neurosyphilis is especially common in people who have HIV. This is because syphilitic sores make it easier to become infected with HIV. Treponema pallidum interacts with HIV in a way that makes it harder to treat the syphilis infection. Those with neurosyphilis and HIV usually need more penicillin injections and have a lower chance for complete recovery
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