It occurs apparently in normal tissues and is associated with degraded calcium metabolism and hypercalcaemia. Metastatic calcification is also noticeable in dystrophic calcification. Since metastatic calcification occurs in normal tissues due to the hypercalcaemia, its causes would include either of the following two groups of causes :- a.) Excessive mobilization of calcium from the bone and b.) Excessive absorption of calcium from the gut. Metastatic calcification occurs because of the excessive binding of inorganic phosphate ions with increased calcium ion due to underlying metabolic derangement.