Often, peritonitis associated with peritoneal dialysis is caused by germs around the tube (catheter). If you're receiving peritoneal dialysis, take the following steps to prevent peritonitis: Wash your hands, including underneath your fingernails and between your fingers, before touching the catheter. Clean the skin around the catheter with an antiseptic every day. Store your supplies in a sanitary area. Wear a surgical mask during your dialysis fluid exchanges. Talk with your dialysis care team about proper care for your peritoneal dialysis catheter. If you've had peritonitis before or if you have peritoneal fluid buildup due to a medical condition such as liver cirrhosis, your doctor may prescribe antibiotics to prevent peritonitis. If you're taking a proton pump inhibitor, your doctor may ask you to stop taking it.