Chemicals Linked To Liver Damage
Exposure to per- and polyfluoroalkyl substances (PFAS) ― a class of widely used synthetic chemicals dubbed "forever chemicals" ― can lead to liver damage and may be a culprit in rising rates of nonalcoholic fatty liver disease (NAFLD), say the authors of a comprehensive evidence review. They found "consistent" evidence for PFAS hepatotoxicity from rodent studies. In addition, exposure to PFAS was found to be associated with markers of liver function in observational studies in people. The review, published online in Environmental Health Perspectives, may be the first systematic analysis of PFAS exposure and liver damage. We cover it extensively on Medscape. Tap the link in bio. Meta-analyses of human studies found that higher levels of alanine aminotransferase (ALT) were significantly associated with exposure to three of the older chemicals — PFOA, PFOS, and PFNA. The "positive" and "convincing" associations between exposure to these synthetic chemicals and higher ALT levels suggest that exposure may contribute to the growing NAFLD epidemic, the researchers write. Exposure to one of the chemicals ― PFOA ― was also associated with higher aspartate aminotransferase (AST) and gamma-glutamyl transferase levels in people. By: https://www.instagram.com/p/CdLUai9OqiQ/?igshid=YmMyMTA2M2Y=