Patients who are immunocompromised are more predisposed to systemic mycoses, but they can develop in otherwise healthy patients. Systemic mycoses can be split between two main varieties, endemic respiratory infections and opportunistic infections. #👽Fungi that can cause systemic infection in people with normal immune function as well as those who are immune-compromised, include: Histoplasma capsulatum (causing histoplasmosis) Coccidioides immitis (causing coccidioidomycosis) Blastomyces dermatitidis (causing blastomycosis) Paracoccidioides brasiliensis (causing paracoccidioidomycosis) Talaromyces marneffei (causing talaromycosis) #😈Opportunistic infections Fungi that only result in systemic infection in immunocompromised or sick people include: Candida species including non-albicans candida (causing candidiasis) Aspergillus species (causing aspergillosis) Cryptococcus (causing cryptococcosis) Zygomycetes (causing zygomycosis). These fungi are found in or on normal skin, decaying vegetable matter, and bird droppings respectively, but not exclusively. They are present throughout the world