What is Spectral karyotype?
Spectral karyotype of a normal cell and cancer cell respectively. • Cancer cells show two fundamental properties: abnormal cell proliferation and a propensity to spread and invade other parts of the body (metastasis). • In normal cells, these functions are tightly controlled by genes that are expressed appropriately in time and place. In cancer cells, these genes are either mutated or are expressed inappropriately. • Cancer is a genetic disease. Genomic alterations that are found in cancer cells range from single-nucleotide substitutions to large-scale chromosome rearrangements, amplifications, and deletions. • Cancers arise from the accumulation of many mutations in many genes. • The mutations that lead to cancer affect multiple cellular functions, including repair of DNA damage, cell division, apoptosis, cellular differentiation, migratory behaviour, and cell-cell contact. By: https://www.instagram.com/p/CZw2-EauWbE/?utm_medium=copy_link