Macromastia refers to enlarged breasts. One of the condition is known as diffuse breast hypertrophy. In this condition, the breast tissue enlarges rapidly during puberty. In addition, the growth of breast tissue is sustained in adulthood. The etiology of hypertrophy is multifactorial. It may be associated with hormonal imbalance and obesity. The treatment involves reduction mammoplasty. Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706054/ Image via: https://europepmc.org/article/pmc/pmc6541761