Location of Abdominal Pain In your abdominal cavity, there are many organs with peritoneum and mesentery. Pathology of any organ can cause pain. Therefore, there are many possible diagnoses for a simple complain of abdominal pain. Abdominal cavity is divided into 9 quadrants to facilitate diagnosis. If we look into each quadrant individually, there are many possible diagnoses for a common and simple abdominal pain. Pain in right upper quadrant may indicate cholecystitis, cholangitis, cholelithiasis, diverticulitis, colitis, hepatitis, liver abscess, embolus, nephrolithiasis, pyelonephritis and others. Pain in epigastrium may indicate cholecystitis, cholangitis, cholelithiasis, myocardial infarction, pericarditis, esophagitis, peptic ulcer, gastritis, pancreatic mass, pancreatitis and others. Pain in left upper quadrant may indicate angina, myocardial infarction, pericarditis, esophagitis, gastritis, peptic ulcer, pancreatic mass, pancreatitis, nephrolithiasis, pyelonephritis and others. Pain in umbilical region may indicate early appendicitis, esophagitis, gastritis, peptic ulcer, small-bowel mass or obstruction, aortic dissection, mesenteric ischemia and others. Pain in right lower quadrant may indicate appendicitis, colitis, diverticulitis, IBD, IBS, ectopic pregnancy, fibroids, ovarian mass, torsion, PID, nephrolithiasis, pyelonephritis and others. Pain in suprapubic region may indicate appendicitis, colitis, diverticulitis, IBD, IBS, ectopic pregnancy, fibroids, ovarian mass, torsion, PID, cystitis, nephrolithiasis, pyelonephritis and others. Pain in left lower quadrant may indicate colitis, diverticulitis, IBD, IBS, ectopic pregnancy, fibroids, ovarian mass, torsion, PID, nephrolithiasis, pyelonephritis and others.