Systemic sclerosis is a multi-organ disease. The dermatological manifestations of systemic sclerosis are: - non-pitting edema of fingers - sclerodactyly - painful digital ulcers - telangiectasias - beak-shaped nose - microstomy - radial furrowing around mouth - calcinosis - anhydrosis - joint contractures Reference: https://academic.oup.com/rheumatology/article/48/suppl_3/iii14/1780608 Image via: https://link.springer.com/article/10.1007/s12016-017-8625-4