#chapter_1
#introduction_To_The_Human_Body
#SKIN
*The skin is the largest organ in the body, accounting for about 15% to 20% of the total body mass, and has the following functions:
• Protection:
against mechanical abrasion and in immune responses, as well as prevention of dehydration.
• Temperature regulation:
largely through vasodilation, vasoconstriction, fat storage, or activation of sweat glands.
• Sensations:
to touch by specialized mechanoreceptors such as pacinian and Meissner’s corpuscles; to pain by nociceptors; and to temperature by thermoreceptors.
• Endocrine regulation:
by secretion of hormones, cytokines, and growth factors, and by synthesis and storage of vitamin D.
• Exocrine secretions:
by secretion of sweat and oily sebum from sebaceous glands.
*The skin consists of two layers:
• Epidermis:
is the outer protective layer consisting of a keratinized stratiied squamous epithelium derived from the embryonic ectoderm.
• Dermis:
is the dense connective tissue layer that gives skin most of its thickness and support, and is derived from the embryonic mesoderm.
*Fascia:
is a connective tissue sheet that may contain variable amounts of fat. It can interconnect structures, provide a conduit for vessels and nerves, and provide a sheath around structures that permits them to slide over one another easily.
*Supericial_fascia:
is attached to and lies just beneath the dermis of the skin and can vary in thickness and density; it acts as a cushion, contains variable amounts of fat, and allows the skin to glide over its surface.
*Deep_fascia:
usually consists of a dense connective tissue, is attached to the deep surface of the supericial fascia, and often ensheathes muscles and divides them into functional groupings.
*Common injuries to the skin include abrasions, cuts, and burns. Burns are classiied as follows:
• First_degree:
burn damage that is limited to the supericial layers of the epidermis; termed a superficial burn, clinically it causes erythema.
• Second_degree:
burn damage that includes all of the epidermis and extends into the superficial dermis; termed, it causes blisters but spares the hair follicles and sweat glands.
• Third_degree:
burn damage that includes all the epidermis and dermis and may even involve the subcutaneous tissue and underlying deep fascia and muscle.
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