Thalassemia is an inherited disorder of blood in which there is the mutation of the genes involved in the Hemoglobine synthesis. This mutation causes defective synthesis of either alpha or beta chains which causes the red cell abnormality. There are two main types of thalassemia: alpha and beta chain thalassemia. The people with this condition results with fatigue, weakness and pallor. Complications includes iron overload, infections, bone deformities, splenomegaly and slowed growth. Peripheral blood film will shows microcytic hypochromic anemia, nucleated RBCs, anisopoikilocytosis and target cells. Picture credit: https://themedicalbiochemistrypage.org/thalassemias-beta-thalassemias/