Cotton wool spots are fundoscopic finding in diabetic retinopathy. These are white patches seen on fundoscopy. Nerve damage secondary to diabetes results in formation of cotton-wool spots. Reference: https://en.wikipedia.org/wiki/Cotton_wool_spots#:~:text=Cotton%20wool%20spots%20are%20an,within%20the%20nerve%20fiber%20layer. Image via: https://www.reviewofophthalmology.com/article/cotton-wool-spots-may-challenge-diagnosis