Loratadine Oral belongs to the class of Antihistamines. Histamine is a naturally produced chemical in response to an allergic reaction. Loratadine Oral is used for the prevention and treatment of allergic conditions like runny nose, itching, watery eyes, sneezing and other cold-like symptoms. This drug is also prescribed for chronic skin itching, hives, hay fever and other allergies. The side effects of Loratadine Oral include - Fatigue and exhaustion - Diarrhea - Rash - Epistaxis - Flu and cold-like symptoms - Dysphonia - Nervousness and anxiety - Dizziness - Insomnia - Dry mouth Loratadine Oral interacts with the following drugs. - Acetaminophen - Aspirin - Ibuprofen - Alprazolam - Duloxetine