What is the role of baloxavir marboxil (Xofluza) in the treatment of influenza?
Role of Baloxavir marboxil in Influenza Treatment This prodrug after converting into Baloxavir by hydrolysis inhibits the activity of endonuclease of Polymerase Acidic (PA) protein present in Influenza virus. This protein plays a crucial role in the viral RNA transcription and hence, replication of virus. Once blocked, the virus fails to undergo replication.