High-grade squamous intraepithelial lesions look somewhat to very abnormal when looked at under a microscope. They are usually caused by chronic infection with certain types of human papillomavirus (HPV) and are found when a Pap test or biopsy is done.

HGSIL is not producing any symptoms. They are found in microscope

Signs and Symptoms of High-grade Squamous Intraepithelial Iesion (HGSIL) • Inter-menstrual bleeding • Postcoital bleeding • Dyspareunia • Heaviness and fullness in the pelvis