Pharmacological Causes of Gynecomastia
Gynecomastia refers to the enlargement of breasts in males. The hormonal imbalance is the basis of development. In addition to pain, the embarrassment may take a toll on mental health. Numerous medications are associated with development of gynecomastia. Common among them are: - Anti-androgens such as spironolactone, finasteride, and flutamide - Anabolic steroids and androgens - Highly active antiretroviral therapy drugs, especially efavirenz - Anxiolytics e.g., diazepam - Stomach-emptying drugs e.g., metoclopramide - Chemotherapeutic agents - Over-the-counter medications for ulcers e.g., cimetidine - Antibiotics - Tricyclic antidepressants Reference: https://www.mayoclinic.org/diseases-conditions/gynecomastia/symptoms-causes/syc-20351793 Image via: https://www.nejm.org/doi/full/10.1056/nejmicm1209166
