When is a bone marrow or lymph node biopsy indicated in the workup of Epstein-Barr virus (EBV) infectious mononucleosis (mono)?
Rarely, if ever, is a bone marrow biopsy or lymph node biopsy needed in patients with EBV infectious mononucleosis. In the diagnosis of EBV infectious mononucleosis, the assessment of lymph node enlargement can be made confidently based on specific EBV antibody testing, and surgery is almost never necessary. [MedScape]
Indications for Bone Marrow Biopsy and Lymph Node Biopsy in Epstein Barr Virus (EBV) Infectious Mononucleosis This procedure is not required in EBV infectious mononucleosis. However, in rare instances bone marrow or lymph node biopsy may be conducted for lymph node enlargement in chronic conditions.
