Abeer Fatimaover 3 years ago

Steps of Atheromatous Plaque Formation

1. Low-density lipoprotein accumulation 2. Oxidation of low-density lipoprotein 3. Recruitment of macrophages and monocytes 4. Uptake of oxidized lipoproteins by macrophages to form form-cells 5. Stabilization of plaque secondary to smooth muscle proliferation and fibrous cap formation. Reference: https://pubmed.ncbi.nlm.nih.gov/10649641/ Image via: https://www.sciencedirect.com/science/article/pii/S1537189116303147