Hi doctors... Could you tell me what's the difference between acid-labile and acid resistant drugs? Thank you💜
Acid labile drug means a drug that is easily destroyed in acidic environment. The Stomach is the main site for drug absorption mainly by oral route. The pH of the stomach is acidic so the absorption of acid labile drugs through stomach is difficult. For this reason, the drugs should be formulated as enteric coated or may be administered through parenteral route.