Gluten-sensitive enteropathy is an immune response to protein present in grains. The reaction takes place in small intestine, resulting in malabsorption disease. The gastrointestinal signs and symptoms of celiac disease are: - Constipation - Diarrhea - Bloating - Fatigue - Weight loss - Abdominal pain - Nausea - Vomiting Other signs and symptoms may include: - Anemia - Osteoporosis - Osteomalacia - Dermatitis herpetiformis - Headache - Fatigue - Numbness - Joint pain - Hyposplenism Reference: https://www.mayoclinic.org/diseases-conditions/celiac-disease/symptoms-causes/syc-20352220 Image via: https://link.springer.com/article/10.1007/s11739-013-1044-5