Angular Cheilitis
Angular cheilitis, also known as angular stomatitis, is an inflammatory condition that affects the corners of the mouth and the oral commissures. It may occur on either only one or on both sides of the mouth and may last for a few days or persist indefinitely. It doesn't have a specific cause but the most common cause is a yeast infection due to dribbling saliva. Other causes include an overhang of upper lip, bacterial infections, dry lips, cold sores and eczematous cheilitis. Poor nutrition, poorly fitted dentures, oral thrush and certain drugs (isotretinoin, acitretin etc) are some of the risk factors of angular cheilitis. The clinical picture includes painful fissures alongwith blisters and erosions with oozing and crusting. The area appears red and slightly swollen with bleeding. Licking the affected area worsens the condition. The treatment depends on the underlying cause. For example, in case of a yeast infection oral antifungals and topical antifungals are effective. Apart from this, frequent application of a thick emollient on the affected area is beneficial too. Image source: healthjade.net
Another cause is lack of cleanliness, Does it occur in men more or women or the same?
Yes, lack of cleanliness is a contributing factor too. When it comes to gender, both males and females are affected equally. There's no specific correlation.