One of the types of non-Hodgkin’s lymphoma is Burkitt lymphoma. It is a fast-growing tumor characterized by impaired immunity which is often fatal. In underdeveloped countries, Burkitt lymphoma occurs in young children as a complication of infectious mononucleosis secondary to EBV infection or malaria. It can also occur in individuals with HIV. Burkitt lymphoma can arise in jaw, facial bones, breast, ovaries, and gastrointestinal tract. It can also spread to central nervous system. Prompt diagnosis is imperative due to its fast spread. Intense chemotherapy can limit the spread of disease thereby increasing life expectancy. Reference: https://www.webmd.com/cancer/lymphoma/burkitt-lymphoma-prognosis-diagnosis-treatments Image via: https://www.msdmanuals.com/professional/hematology-and-oncology/lymphomas/burkitt-lymphoma
It's also associated with genetic defects like t(8; 22), t(8; 14), t(2; 8 ). These defects increase c-myc concentration. Which responsible for increases in mitosis and so cell proliferation accelerate.
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