Pemberton's sign or Pemberton maneuver is a physical examination tool used to evaluate venous obstruction in patients with goiter. The sign is positive when bilateral arm elevation causes facial plethora marked by the presence of facial congestion and cyanosis, as well as respiratory distress after approximately one minute. Moreover, It has been attributed to a “cork effect” resulting from the thyroid obstructing the thoracic inlet, thereby increasing pressure on the venous system. https://www.grepmed.com/images/4691/physicalexam-pembertons-clinical-photo-sign