Ape hand is a condition in which movements of the thumb are severely limited. The thumb may have limited extension and flexion. This means the thumb can only be moved away from and towards the hand in the plane of the palm. The thumb will also have very limited or no ability to abduct or oppose. This means it cannot be moved in and out of the palm to pinch or grasp.Ape hand is usually the result of median nerve palsy, which is commonly caused by deep injury to the wrist or forearm. This can impair the function of the thenar muscles.