Paroxysmal Nocturnal Hemoglobinuria (PNH)
CD55/CD59 proteins also known as decay accelerating factors found on surface of RBCs protect them from complement-mediated hemolysis. PNH is a deficiency in glycosylphosphatidylinositol-anchor molecules that decay factor attachment or binding to RBCs, resulting in complement mediated hemolysis and thrombosis. How does patients present? PNH can manifest as iron deficiency anemia, episodic dark urine, venous thrombosis (most commonly mesentric and hepatic vein thrombosis), pancytopenia and abdominal pain. Most accurate diagnostic test is CD55/CD59 absence via flow cytometery. Prednisone is the best initial therapy. Allogenic bone marrow transplant is curative. Eculizumab, a complement inhibitor can be used for hemolysis and thrombosis.
Abdominal aortic aneurysmMental and physical health are interconnected. We, as a society, need to work on emphasizing the importance of the two. This would prevent people developing physical and mental diseases at earlier and earlier ages.Treatment of degenerative joint diseaseGet Glowing Skin and Clear FaceHypocalcemiaMarfan syndromePhenylketonuriaSymptoms of neimann pick diseaseThe 29th World Congress on Nutrition and Food Sciences, held on September 15-16, 2025, in Amsterdam, Netherlands, was a landmark event in the fields of nutrition and food sciences. This congress gathered leading experts, researchers, policymakers, and practitioners from across the globe, providing a vibrant platform for the exchange of ground breaking research, innovative ideas, and best practices in nutrition and food science. With a focus on tackling contemporary challenges in health and nutrition, the congress covered a wide range of topics, from the latest advancements in nutritional science to strategies for promoting sustainable food systems and preventing chronic diseases. Attendees engaged in thought-provoking discussions, participated in interactive workshops, and had ample opportunities to network with peers across diverse disciplines. Theme: Nutrition for a Resilient World: Advances, Challenges and Opportunities