Vitiligo

Vitiligo is an acquired pigmentary dermatological disorder that is characterised by confined macule and patches of depigmentation. The precise pathophysiology is not understood but it is speculated that this condition results from progressive destruction of melanocytes. Many theories regarding the destruction exist which include autoimmune mechanisms, cytotoxic mechanisms, intrinsic melanocyte defects, oxidant-antioxidant mechanisms, and neural mechanisms. To learn more about this topic you can visit: https://emedicine.medscape.com/article/1068962-overview#a6