Raynaud’s phenomenon refers to decreased flow of blood to the fingers secondary to spasm of blood vessels. Nose, ears, nipples, toes, or knees can also be affected. The spasm of blood vessels may occur due to emotional tension, stress, or cold. Primary Raynaud’s phenomenon has isolated occurrence. On the other hand, this phenomenon may be associated with variety of disorders such as scleroderma, systemic lupus erythematosus, rheumatoid arthritis, Sjogren syndrome, CREST syndrome, polymyositis, pulmonary hypertension, and cryoglobulinemia, among others. Primary Raynaud’s phenomenon is less severe than secondary form. The most common age of primary form is 15 to 25 years. The manifestations of Raynaud’s phenomenon are: - Pale, white, or blue fingers on exposure to stress, cold, or emotional tension - Swollen, painful hands - Sores on fingertips - Gangrenous fingers There is no definitive treatment of Raynaud’s phenomenon. However, it can be prevented by avoiding the stimuli that trigger the condition. Reference: https://www.hopkinsmedicine.org/health/conditions-and-diseases/raynauds-phenomenon#:~:text=Raynaud's%20phenomenon%20is%20a%20problem,%2C%20stress%2C%20or%20emotional%20upset. Image courtesy: https://pharmaceutical-journal.com/article/news/drug-induced-raynauds-phenomenon-probably-underestimated