D K MEDILIFEabout 7 years ago
Say TRUE OR FALSE Can methotrexate is used in PREGNANCY?
Top rated comment
about 7 years ago
This drug causes teratogenic effects, embryotoxicity, abortion, and fetal defects in humans. High dose methotrexate is also used in the termination of intrauterine pregnancy and the treatment of ectopic pregnancy.
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about 7 years ago
Methotrexate is a folic acid antagonist that inhibits dihydrofolate reductase, resulting in a block in the synthesis of thymidine and inhibition of DNA synthesis.
about 7 years ago
Yes, It should inhibit folic acid metabolism in fetus and can cause neural tube defect like abnormality....
about 7 years ago
F. it stops cellular growth and differentiation; because it alters de cell cycle, so the answer is pretty clear
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