Hanin Kaaabout 7 years ago

A 62-year-old man presents with an ulcerated, encrusted, and infiltrating lesion on the sun-exposed dorsal aspect of a finger (shown in the image). A biopsy reveals squamous cell carcinoma. The metastatic potential of this neoplasm would be enhanced by upregulation of the gene for which of the following proteins? 1. Collagen type IV 2. Desmin 3. E-cadherin 4. Glutathione peroxidase 5. Plasminogen activator. Source ;medicmad