𝗕𝘂𝗿𝗸𝗶𝘁𝘁'𝘀 𝗹𝘆𝗺𝗽𝗵𝗼𝗺𝗮
⭕It is a type of 𝗡𝗢𝗡-𝗛𝗢𝗗𝗚𝗞𝗜𝗡'𝗦 𝚕𝚢𝚖𝚙𝚑𝚘𝚖𝚊𝚜. About 1/3 𝗡𝗢𝗡-𝗛𝗢𝗗𝗚𝗞𝗜𝗡'𝗦 lymphomas are 𝐁𝐮𝐫𝐤𝐢𝐭𝐭'𝐬 𝐥𝐲𝐦𝐨𝐡𝐨𝐦𝐚. ⭕It is a 𝗛𝗜𝗚𝗛𝗟𝗬 𝗔𝗚𝗚𝗥𝗘𝗦𝗦𝗜𝗩𝗘 B-cell tumor. ⭕Found mainly in tropical parts of the globe. ⭕There are 2 subtypes of the disease🔻: 1-𝐀𝐟𝐫𝐢𝐜𝐚𝐧 𝐞𝐧𝐝𝐞𝐦𝐢𝐜 2- 𝐒𝐩𝐨𝐫𝐚𝐝𝐢𝐜. ⭕Both endemic and sporadic variants are charchtarized by transloctaion involving chromosmes 8 and 14 , which causes deregulation of the c-myc gene , resulting in cell prolefiration. ⭕Characterized by the presence of "𝘀𝘁𝗮𝗿𝗿𝘆 𝘀𝗸𝘆" histological appearance. ⭕The picture here is for a child affected with the endemic subtype which affects mainly the jaw of the patient. ♦️If you have any additional notes feel free to put it in the comments👇👇.
Excellent work by you 👍. Endemic form is associated with EBV(Ebsten bar virus)& Malaria.