Medicaltalks about 2 months ago

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Prosthetics femur and tibia replacements due to an osteosarcoma of the bone!! 🦴⁣

⁣ Osteosarcoma is a malignant, osteoid and bone-forming tumor arising from mesenchymal stem cells (osteoblasts) located in the periosteum of the bone.⁣ The primary tumor almost always arises from the metaphyses of long bones (particularly distal femur and proximal tibia) — which matches the case above.⁣ It can metastasize (spread) to the lungs, skeletal system, and regional lymph nodes.⁣ Clinically it frequently first manifests with pain (progressive, worsens at night and with activity); swelling after trauma to the bone (tissue mass that is tender to palpation and accompanied by erythema), limping and decreased range of motion, and B symptoms (fever, night sweats, and weight loss).⁣ ⁣ A complete radical, surgical, en bloc resection of the cancer with neoadjuvant and adjuvant polychemotherapy, is the treatment of choice in osteosarcoma. Although about 90% of patients are able to have limb-salvage surgery, complications, particularly infection, prosthetic loosening and non-union, or local tumor recurrence may cause the need for further surgery or amputation.⁣ Limb-sparing procedures should be attempted, but amputation may be necessary for definitive resection.⁣ Photo credit @alberto_tostes