MEDizzy
MEDizzy
Neonatal Lupus

Neonatal Lupus

A baby boy born to apparently healthy parents had a bright red rash over his face within 2 hours after birth (Panel A). He also had clinical features consistent with trisomy 21, which was confirmed by karyotyping. The initial laboratory tests showed a hemoglobin level of 14 g per deciliter and a platelet count of 24,000 per cubic millimeter. An electrocardiogram at 4 weeks of age showed normal sinus rhythm, and the rash was reduced (Panel B). A complete blood count showed a white-cell count of 4500 per cubic millimeter with a normal differential count; the hemoglobin level was 8.8 g per deciliter, the platelet count 79,000 per cubic millimeter, the aspartate aminotransferase level 108 U per liter, and the alanine aminotransferase level 115 U per liter. Serologic testing by means of a multiplex bead assay (BioPlex 2200; Bio-Rad Laboratories) was strongly positive for SSA (Ro) and SSB (La) (for each test: antibody index units, >8; negative result is <1), confirming the diagnosis of neonatal lupus. By the time the patient was 6 months old, the rash had resolved without specific therapy (Panel C), and the levels of hemoglobin, platelets, and liver enzymes had normalized. The child's mother had not received a diagnosis of any autoimmune disorder previously. After further questioning, she described having dry eyes for more than 1 year, which required the frequent use of artificial tears. She was referred to a rheumatologist and received a diagnosis of Sjögren's syndrome. Maternal antibodies crossing the placenta can lead to the clinical manifestations of neonatal lupus. Mothers with only mild or no symptoms of autoimmune disease may be at substantial risk for the development of an overt autoimmune disorder, most commonly Sjögren's syndrome or systemic lupus erythematosus. Any future children of these parents are at risk for neonatal lupus and congenital heart block.

72
Other commentsSign in to post comments. You don't have an account? Sign up now!
over 5 years ago

This is candida albicans can be cured

over 5 years ago

Candida

over 5 years ago

Candida

7 days ago

Living with Lupus is often a battle not just against the illness itself, but also against the emotional weight of uncertainty, fatigue, and the toll of long-term medications. For one courageous woman, that battle began in 2013. Diagnosed after Lupus had already affected her joints and internal organs, she was quickly placed on medication that initially helped. But as time went on, her health declined again this time with more frequent flare-ups and increasingly difficult side effects. Like many others with chronic illness, she faced the crushing weight of hopelessness. Each day became harder than the last, and conventional treatments no longer offered the comfort they once did. But in March 2020, at her lowest point, she made a decision that changed everything.Out of desperation and with a healthy dose of skepticism she turned to NaturePath Herbal Clinic, hoping their natural Lupus treatment might offer at least some relief. What happened next went far beyond her expectations.After completing a six-month herbal program, her flare-ups stopped entirely. Her energy returned. The chronic pain that had defined her daily life began to fade. For the first time in years, she felt like herself again. Not just alive but truly living.Her story is not just one of healing; it’s one of resilience, open-mindedness, and the courage to try something new when all else fails. By sharing her journey, she hopes to offer something priceless to others living with Lupus: hope.This treatment has been a true breakthrough for her. If you’re searching for a safe, natural, and effective alternative, I genuinely recommend giving this a chance.”www.naturepathherbalclinic.com or email them at info@naturepathherbalclinic.com

Recent MCQs















Show more MCQs

Recent flashcard sets















Show more flashcards