Dr.Sanaover 7 years ago

BURKITT LYMPHOMA-HISTOLOGY

👉Diffuse growth 👉Areas of necrosis and hemorrhage are usually seen 👉"Starry sky" or "moth eaten" appearance, due to blue neoplastic cells and histiocytes engulfing debris from apoptotic tumor cells 👉Neoplastic cells are motonous, medium sized, with squared-off basophilic cytoplasm, which may be plasmacytoid 👉Nuclei are uniform, round to oval, slightly indented, with coarse chromatin, 2 - 5 small centrally located basophilic nucleuoli 👉Numerous mitotic figures