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USMLE
Diseases of the Endocrine System
A patient examined by a doctor has a positive Trousseau’s sign and a positive Chvostek’s sign. Of the following, what is the mechanism of action of their disease process?
Explanation
ExplanationA positive Chvostek’s sign and positive Trousseau’s sign indicate hypoparathyroidism. Hypoparathyroidism causes hypocalcemia, and hypocalcemia causes a reduction in the potential difference at the neuromuscular junction.
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