It is secreted by cells of the proximal tubule

Its secretion leads to loss of sodium and water from plasma

Its secretion is stimulated by increased mean renal arterial pressure

It converts angiotensinogen to angiotensin I

An 18-year-old male presents with muscle weakness, cramps, and tetany. Blood pressure is normal and no edema is present. Laboratory analysis reveals hypokalemic alkalosis, hyperaldosteronism, and high plasma renin activity, diagnostic of Bartter’s syndrome. Which of the following statements about renin is true?