MEDizzy - A nurse is preparing to administer indomethacin (Indocin®)

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Neonatal and High-Risk Neonatal Management

A nurse is preparing to administer indomethacin (Indocin®) to an infant diagnosed with patent ductus arteriosus (PDA). By which route should the nurse expect to administer the indomethacin for this infant?

ExplanationThe preferred administration route of indomethacin for treatment of a PDA is IV, so the medication can quickly enter the vascular system. Indomethacin is given to infants with PDA because it often stimulates closure of the defect. Although indomethacin can be administered orally and rectally, the onset of action is delayed. Indomethacin is not administered IM.