A 21-year-old man is diagnosed with poststreptococcal glomerulonephritis. Which of the following is likely to be found in his urine?
ExplanationThe hallmark of glomerular renal disease is microscopic hematuria and proteinuria. IgA nephropathy and sickle cell disease are the exception to this when gross hematuria may be present. Proteinuria may be heavy (>3 g/24 hours) or lower quantity with microalbuminuria (30–300 mg/24 hours) depending on the underlying disease or site of the immune lesion. Patients with post-streptococcal glomerulonephritis often have pyuria, but cultures are not expected to be positive as the infection is usually skin or mucosal, and it is the immune reaction that drives the renal lesion.