MEDizzy - Drugs that block prostaglandin production reduce

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Pharmacological Therapies VI

Drugs that block prostaglandin production reduce inflammation. Which enzyme responsible for prostaglandin production is affected by these medications?

ExplanationNonsteroidal anti-inflammatory drugs (NSAIDs) reduce pain by blocking the undesirable effects of prostaglandins. They inhibit the enzyme cyclooxygenase and prevent the formation of prostaglandins. Choice 1 is incorrect because NSAIDs have no effect on arachidonic acid. Choice 2 is an alcohol related to fats and included in lipids; it is not involved in prostaglandin production. (Cholesterol is a sterol.) Choice 3 acts to aggregate platelets and is a potent vasoconstrictor.