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USMLE
The Nervous System (The Special Senses)
Which statement best describes the underlying basis of the dark current in the outer segment of the photoreceptors?
Explanation
ExplanationcGMP-dependent sodium channels in the outer portions of the rods and cones allow sodium ions to pass from the extracellular space to the intracellular space of the photoreceptor. This process results in a membrane potential that is somewhat lower than the resting membrane potential of a typical neuron. The movement of the sodium ions and resulting electrical potential change as a result of this enhanced permeability is known as the dark current.
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