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USMLE
Nephrology (Case 1-12)
All of the following should be considered in the differential diagnosis now EXCEPT:
Explanation
ExplanationThe correct answer is A. Minimal change disease usually presents with clinical signs and symptoms of nephrotic syndrome and not gross hematuria. All of the other diseases are associated with hematuria, either microscopic or gross. Henoch-Schönlein purpura, poststreptococcal glomerulonephritis, IgA nephropathy, and membranoproliferative glomerulonephritis all have more nephritic features with active urinary sediments (dysmorphic red cells, red cell casts, and granular casts, white cells and protein in the urine). Also, these diseases have a similar pathologic process in which immune complexes deposit in the glomeruli, resulting in glomerulonephritis
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