MEDizzy - If the renal clearance of substance X is 300 ml/min and the

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The Body Fluids & Kidney (II)

If the renal clearance of substance X is 300 ml/min and the glomerular filtration rate is 100 ml/min, it is most likely that substance X is

ExplanationIf the renal clearance is greater than the GFR, this implies that there must be secretion of that substance into the renal tubules. A substance that is freely filtered and not secreted or reabsorbed would have a renal clearance equal to the GFR.