MEDizzy - A 7-year-old male presents with sudden onset of gross

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Nephrology Part I

A 7-year-old male presents with sudden onset of gross hematuria and edema. Blood pressure is 130/90 mmHg. Investigations results; blood urea 160mg/dl, low C3 level, and urinalysis shows RBC casts. He had history of treatment for acute tonsillitis with penicillin for 10 days. Which of the following is the MOST likely diagnosis?

ExplanationAcute post-streptococcal glomerulonephritis (APSGN) is a classic example of the acute nephritic syndrome characterized by the sudden onset of gross hematuria, edema, hypertension, and renal dysfunction. It is one of the most common glomerular causes of gross hematuria in children and is a major cause of morbidity in group A β-hemolytic streptococcal infection.