MEDizzy - You are treating a 48-year-old man for major depression. His

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Chronic conditions

You are treating a 48-year-old man for major depression. His medical history includes a head injury several years ago that has left him with a seizure disorder. Which of the following antidepressants would be contraindicated?

ExplanationWhile many of the newer antidepressants are well-tolerated, physicians should be familiar with the adverse effects and contraindications for their use. Hypertension is a relative contraindication to venlafaxine. Patients experiencing hypersomnia and motor retardation should avoid mirtazapine. Patients who report agitation and insomnia should avoid bupropion and venlafaxine. Mirtazapine and tricyclic antidepressants like amitriptyline are less preferred for patients with obesity. Bupropion is contraindicated for patients with seizure disorder.