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Hematology

A 5-year-old boy is admitted because he bled profusely when he lost his first baby tooth. After a workup, he is diagnosed as having classic hemophilia. His mother asks the nurse if his two younger sisters will also develop hemophilia. What is the best answer for the nurse to give?

“They will not develop the disease.”“Statistically, one of them is likely to develop the disease.”“They are not likely to get the disease, but they may be carriers.”“If it doesn’t show up by the time they start school, they are unlikely to develop the condition.”

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ExplanationHemophilia is carried on the X chromosome and causes disease when it appears in combination with the Y chromosome in the male. Answer 1 is a true statement, but it is not complete and, therefore, not the best answer.

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