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USMLE
The Body Fluids and Kidneys (I)
A 62-year-old woman has previously had a unilateral nephrectomy after diagnosis of renal carcinoma. Her GFR (estimated from creatinine clearance) is 50 ml/min, her urine flow rate is 2.0 ml/min, and her plasma glucose concentration is 200 mg/100 ml. If she has a kidney transport maximum for glucose of 150 mg/min, what would be her approximate rate of glucose excretion?
Explanation
ExplanationThe filtration rate of glucose in this example is GFR (50 ml/min) × plasma glucose concentration (200mg/100 ml, or 2 mg/ml) = 100 mg/min. Because the transport maximum for glucose in this example is 150mg/min, all of the filtered glucose would be reabsorbed and the renal excretion rate for glucose would be zero.
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