MEDizzy - A 25-year-old female patient presents with massive

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Combined Hematology

A 25-year-old female patient presents with massive haemorrhage. You are working in the hospital blood bank and are asked to prepare 2 units each of Red cells and Fresh Frozen Plasma (FFP) when the result of the group and save is available. The patient's sample is grouped as B RhD negative. You manage to procure some Group B red cells from the fridge but there is no Group B FFP available. FFP from a donor of which blood group would be best to give?

ExplanationC. The universal donor of fresh frozen plasma is AB RhD negative blood This patient is blood group B RhD negative, meaning her red cells possess B antigens only from the ABO grouping, and she naturally produces anti-A antigens in her plasma. Therefore, she needs to receive red cells with only B antigen or no antigens at all (i.e. Groups B or O) but needs to receive FFP that does not have anti-B in it. Group O donors naturally produce anti-A and anti-B, Group A donors naturally produce only anti-B, so she can only receive FFP from groups B or AB. Group AB is the universal donor for FFP because they produce neither anti-A or anti-B and is therefore compatible with all ABO groups. In many cases the RhD status would not matter for blood transfusion, however as this is a woman of childbearing age who is RhD negative, she should receive RhD negative blood in order to avoid problems with future pregnancies in which the fetus is RhD positive.